Reduced expression of inflammasome complex components in cluster headache.

Erdi SahinZerrin KaraaslanElif ŞanlıÖzlem Timirci KahramanCanan UlusoyElif Kocasoy OrhanEsme EkizoğluCem İsmail KüçükaliErdem TüzünBetül Baykan

Published in: Headache (2022)

Our results support the involvement of the IL-1β system in attacks of CH. However, the components of the inflammasome complex are suppressed in the peripheral blood and do not appear to play a role in the pathophysiology of CH. These findings argue against a potential biomarker value of the inflammasome complex in CH.

Keyphrases

peripheral blood
room temperature
poor prognosis
binding protein
long non coding rna