Prognostic 7-SLC-Gene Signature Identified via Weighted Gene Co-Expression Network Analysis for Patients with Hepatocellular Carcinoma.
Lingfeng XiongYongping LuoTianbai YuanWeipeng LinBohui LinChen WuYuyou DuanYimeng OuPublished in: Journal of oncology (2023)
The 7-SLC-gene prognostic signature established in this study helped predict the prognosis, and was also correlated with the tumor immune status and infiltration of different immune cells in the tumor microenvironment. The current findings may provide important clinical indications for proposing a novel combination therapy consists of targeted anti-SLC therapy and immunotherapy for HCC patients.
Keyphrases
- network analysis
- combination therapy
- copy number
- genome wide
- end stage renal disease
- genome wide identification
- newly diagnosed
- ejection fraction
- poor prognosis
- magnetic resonance
- magnetic resonance imaging
- peritoneal dialysis
- prognostic factors
- stem cells
- cancer therapy
- gene expression
- computed tomography
- bone marrow
- long non coding rna
- genome wide analysis
- binding protein
- drug delivery