Production of amphiregulin and recovery from influenza is greater in males than females.

Meghan S VermillionRebecca L UrsinDenise I T KuokLandon G Vom SteegNicholas WohlgemuthOlivia J HallAshley L FinkEric SasseAndrew NelsonRoland NdehSharon McGrath-MorrowWayne MitznerMichael C W ChanAndrew PekoszSabra L Klein

Published in: Biology of sex differences (2018)

Taken together, these data show that elevated levels of testosterone and AREG, either independently or in combination, improve resilience (i.e., repair and recovery of damaged tissue) and contribute to better influenza outcomes in males compared with females.

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