Resource limited centres can deliver treatment for children with acute lymphoblastic leukaemia with risk-stratified minimal residual disease based UKALL 2003 protocol with no modification and a good outcome.
Harsha Prasada LashkariMoideen FaheemSridevi Hanaganahalli BasavaiahKamalakshi G BhatJayatheerth JoshiNutan KamathShivali AhlawatPrashantha BPublished in: Expert review of hematology (2020)
It is feasible to deliver chemotherapy as per the UKALL2003 protocol without any modifications in resource-limited setting. The survival rates have significantly improved over the years in our center from 5 years EFS of 60% in 2010 and now to 3 year EFS of 85%. It is important to note that there was no treatment abandonment in our cohort.