Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection.
Olalekan Lee AiyegbusiJessica K RoydhouseSamantha Cruz RiveraPaul KamudoniPeter SchacheRoger WilsonRichard StephensMelanie Jane CalvertPublished in: Nature communications (2022)
Patient-reported outcomes (PROs) are used in clinical trials to provide evidence of the benefits and risks of interventions from a patient perspective and to inform regulatory decisions and health policy. The collection of PROs in routine practice can facilitate monitoring of patient symptoms; identification of unmet needs; prioritisation and/or tailoring of treatment to the needs of individual patients and inform value-based healthcare initiatives. However, respondent burden needs to be carefully considered and addressed to avoid high rates of missing data and poor reporting of PRO results, which may lead to poor quality data for regulatory decision making and/or clinical care.
Keyphrases
- patient reported outcomes
- healthcare
- quality improvement
- electronic health record
- clinical trial
- public health
- big data
- decision making
- end stage renal disease
- case report
- mental health
- primary care
- chronic kidney disease
- palliative care
- risk factors
- human health
- data analysis
- randomized controlled trial
- climate change
- machine learning
- social media
- open label
- chronic pain
- patient reported
- artificial intelligence