Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease.
Thomas KremerKirsten I TaylorJuliane Siebourg-PolsterThomas GerkenAndreas StaempfliChristian CzechJuergen DukartDouglas GalaskoTatiana ForoudLana M ChahineChristopher S CoffeyTanya SimuniDaniel WeintraubJohn SeibylKathleen L PostonArthur W TogaCaroline M TannerKenneth MarekSamantha J HuttenSebastian DziadekClaudia TrenkwalderGennaro PaganoBrit MollenhauerPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
HVA and DOPAC CSF levels mirrored nigrostriatal pathway damage, confirming the central role of dopaminergic degeneration in early PD. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.