Challenges of access to kidney care for children in low-resource settings.
Mignon I McCullochValerie Ann LuyckxBrett CullisSimon J DaviesFredric O FinkelsteinHui Kim YapJohn FeehallyWilliam E SmoyerPublished in: Nature reviews. Nephrology (2020)
Kidney disease is a global public health concern across the age spectrum, including in children. However, our understanding of the true burden of kidney disease in low-resource areas is often hampered by a lack of disease awareness and access to diagnosis. Chronic kidney disease (CKD) in low-resource settings poses multiple challenges, including late diagnosis, the need for ongoing access to care and the frequent unavailability of costly therapies such as dialysis and transplantation. Moreover, children in such settings are at particular risk of acute kidney injury (AKI) owing to preventable and/or reversible causes - many children likely die from potentially reversible kidney disease because they lack access to appropriate care. Acute peritoneal dialysis (PD) is an important low-cost treatment option. Initiatives, such as the Saving Young Lives programme, to train local medical staff from low-resource areas to provide care for AKI, including acute PD, have already saved hundreds of children. Future priorities include capacity building for both educational purposes and to provide further resources for AKI management. As local knowledge and confidence increase, CKD management strategies should also develop. Increased awareness and advocacy at both the local government and international levels will be required to continue to improve the diagnosis and treatment of AKI and CKD in children worldwide.
Keyphrases
- acute kidney injury
- chronic kidney disease
- end stage renal disease
- healthcare
- young adults
- public health
- peritoneal dialysis
- palliative care
- quality improvement
- liver failure
- cardiac surgery
- emergency department
- low cost
- clinical trial
- mesenchymal stem cells
- intensive care unit
- chronic pain
- bone marrow
- hepatitis b virus
- electronic health record
- global health