Association between gastroesophageal reflux disease and colorectal cancer risk: a population-based cohort study.
Je-Ming HuJia-Jheng WuChih-Hsiung HsuYong-Chen ChenYu-Feng TianPi-Kai ChangChao-Yang ChenYu-Ching ChouChien-An SunPublished in: International journal of colorectal disease (2021)
In conclusion, this nationwide population-based cohort study supports the hypothesis that GERD was associated with a significantly increased risk of CRC. Our findings warrant still further investigation of the underlying mechanisms related to carcinogenic effect of GERD on colorectal carcinoma.