An 18-month multimodal intervention trial for preventing dementia: J-MINT PRIME Tamba.
Yutaro OkiTohmi OsakiRyoko KumagaiShunsuke MurataHaruhi EnchoRei OnoHisafumi YasudaHisatomo KowaPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT) PRIME Tamba was a randomized controlled trial to prevent dementia. We provided a multifactorial intervention based on the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) trial methodology. The primary outcome, the cognitive composite score, improved with our intervention. Executive function/processing speed and memory improved in the intervention group. Intervention adherence was high, and no serious adverse events occurred.