Efficacy and Safety of Dexmedetomidine Compared to Other Needle-Free Pharmacological Sedation Methods in Pediatric Patients Undergoing Imaging Procedures.
Mohammed Alsabri Hussein AlsabriAbdelrahman AbdelshafiAhmed Bostamy ElsnhoryNoha Samir SelimAlaa Bostamy ElsnhoryDouaa AlbelalFatima AkramAlaa Ahmed ElshanbaryPublished in: Pediatric emergency care (2024)
Dexmedetomidine demonstrates effectiveness in pediatric MRI/CT sedation, offering advantages over midazolam and similar efficacy to chloral hydrate. Careful cardiovascular monitoring is essential during administration, particularly in patients with congenital heart disease. Sublingual and intranasal administration of dexmedetomidine is a viable option with high bioavailability. This meta-analysis contributes valuable insights into refining sedation protocols for pediatric imaging procedures, emphasizing efficacy and safety considerations.
Keyphrases
- systematic review
- patients undergoing
- high resolution
- end stage renal disease
- cardiac surgery
- mechanical ventilation
- contrast enhanced
- randomized controlled trial
- magnetic resonance imaging
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- meta analyses
- ultrasound guided
- intensive care unit
- diffusion weighted imaging
- pet ct
- positron emission tomography