Effects of Vitamin D Supplementation on Renin and Aldosterone Concentrations in Patients with Advanced Heart Failure: The EVITA Trial.
Zittermann ArminJana B ErnstSylvana ProkopUwe FuchsJens DreierJoachim KuhnCornelius KnabbeJochen BörgermannHeiner K BertholdStefan PilzIoanna Gouni-BertholdJan F GummertPublished in: International journal of endocrinology (2018)
In patients with advanced heart failure treated according to evidence-based guidelines, vitamin D supplementation did not significantly influence parameters of the RAAS in the entire study cohort but was associated with an increase in plasma renin concentrations in the subgroup with low baseline 25-hydroxyvitamin D concentrations.