Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo-controlled, randomized phase III clinical trial (LIBERTY AD CAFÉ).
Marjolein de Bruin-WellerD ThaçiC H SmithK ReichM J CorkA RadinQ ZhangB AkinladeA GadkariL EckertT HultschZ ChenG PirozziN M H GrahamB ShumelPublished in: The British journal of dermatology (2018)
Dupilumab + TCS significantly improved signs and symptoms of atopic dermatitis and QoL in adults with a history of inadequate response to/intolerance of CsA, or for whom CsA treatment was medically inadvisable. No new safety signals were identified.