Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
Gustavo PradillaJonathan J RatcliffAlex J HallBenjamin R SavilleJason W AllenGiorgio PaulonAnna McGlothlinRoger J LewisMark FitzgeraldAngela F CaveneyXiao T LiMark BainJoao GomesBrain JankowitzGeorgios ZenonosBradley J MolyneauxJason DaviesAdnan SiddiquiMichael R ChicoineSalah G KeyrouzJonathan A GrossbergMitesh V ShahRanjeet SinghBradley N BohnstedtMichael FrankelDavid W WrightDaniel L Barrownull nullnull nullPublished in: The New England journal of medicine (2024)
Among patients in whom surgery could be performed within 24 hours after an acute intracerebral hemorrhage, minimally invasive hematoma evacuation resulted in better functional outcomes at 180 days than those with guideline-based medical management. The effect of surgery appeared to be attributable to intervention for lobar hemorrhages. (Funded by Nico; ENRICH ClinicalTrials.gov number, NCT02880878.).