Nucleolar protein 10 (NOP10) predicts poor prognosis in invasive breast cancer.

Khloud A ElSharawyMaryam AlthobitiOmar J MohammedAbrar I AljohaniMichael S TossAndrew R GreenEmad A Rakha

Published in: Breast cancer research and treatment (2020)

High NOP10 expression is a poor prognostic biomarker in BC and its expression can help in predicting chemotherapy resistance. Functional assessments are necessary to decipher the underlying mechanisms and to reveal its potential therapeutic values in various BC subtypes especially in the aggressive TNBC class.

Keyphrases

poor prognosis
long non coding rna
single cell
genome wide
binding protein
squamous cell carcinoma
gene expression
dna methylation
locally advanced
young adults
radiation therapy
amino acid
rectal cancer