Enhancing the production of cephalosporin C through modulating the autophagic process of Acremonium chrysogenum.

Honghua LiPengjie HuYing WangYuanyuan PanGang Liu

Published in: Microbial cell factories (2018)

Our results demonstrated inducible expression of Acatg8 and disruption of Acatg8 remarkably increased cephalosporin C production. This study provides a promising approach for yield improvement of cephalosporin C in A. chrysogenum.

Keyphrases

gram negative
poor prognosis
cell death
signaling pathway
binding protein
long non coding rna