Management of unruptured incidentally found intracranial saccular aneurysms.
Vikram A MehtaCharis A SpearsJihad AbdelgadirTimothy Y WangEric W SankeyAndrew GriffinC Rory GoodwinAli ZomorodiPublished in: Neurosurgical review (2020)
Unruptured intracranial saccular aneurysms occur in 3-5% of the general population. As the use of diagnostic medical imaging has steadily increased over the past few decades with the increased availability of computed tomography (CT) and magnetic resonance imaging (MRI), so has the detection of incidental aneurysms. The management of an unruptured intracranial saccular aneurysm is challenging for both patients and physicians, as the decision to intervene must weigh the risk of rupture and resultant subarachnoid hemorrhage against the risk inherent to the surgical or endovascular procedure. The purpose of this paper is to provide an overview of factors to be considered in the decision to offer treatment for unruptured intracranial aneurysms in adults. In addition, we review aneurysm and patient characteristics that favor surgical clipping over endovascular intervention and vice versa. Finally, the authors propose a novel, simple, and clinically relevant algorithm for observation versus intervention in unruptured intracranial aneurysms based on the PHASES scoring system.
Keyphrases
- middle cerebral artery
- internal carotid artery
- magnetic resonance imaging
- computed tomography
- subarachnoid hemorrhage
- contrast enhanced
- randomized controlled trial
- end stage renal disease
- brain injury
- coronary artery
- optic nerve
- ejection fraction
- positron emission tomography
- chronic kidney disease
- newly diagnosed
- dual energy
- high resolution
- primary care
- healthcare
- image quality
- endovascular treatment
- peritoneal dialysis
- patient reported outcomes
- case report
- smoking cessation
- loop mediated isothermal amplification
- abdominal aortic aneurysm
- replacement therapy
- aortic dissection
- patient reported