Long-term Ovariectomy Reduces Tolerance of Rats to Myocardial Ischemia-reperfusion Injury.

Published in: International journal of endocrinology and metabolism (2023)

The long-term deficiency of estrogen increased the expression of iNOS and decreased the expression of eNOS in the heart tissue of OVX rats. Imbalanced NOS expressions were associated with exacerbated responses to M/IR injury in OVX rats.

Keyphrases

poor prognosis
ischemia reperfusion injury
nitric oxide synthase
heart failure
oxidative stress
nitric oxide
left ventricular
long non coding rna
signaling pathway
estrogen receptor