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Therapeutic targeting at genome mutations of liver cancer by the insertion of HSV1 thymidine kinase through Cas9-mediated editing.

Muhamuda KaderWei SunBao-Guo RenYan-Ping YuJunyan TaoLesley M FoleySilvia LiuSatdarshan P MongaJian-Hua Luo
Published in: Hepatology communications (2024)
Our studies suggested that mutation targeting may hold promise as a versatile and effective approach to treating liver cancers.
Keyphrases
  • crispr cas
  • genome editing
  • cancer therapy
  • big data
  • genome wide
  • gene expression
  • tyrosine kinase
  • machine learning
  • herpes simplex virus
  • case control
  • drug delivery
  • deep learning