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Integration of genome-wide association study and expression quantitative trait loci data identifies AIM2 as a risk gene of periodontitis.

Wenjing LiQiwen ZhengHuanxing MengDafang Chen
Published in: Journal of clinical periodontology (2020)
Our findings implicate that AIM2 is a susceptibility gene, expression of which in gingiva may influence periodontitis risk. Further functional investigation of AIM2 may provide new insight for periodontitis pathogenesis.
Keyphrases
  • genome wide association study
  • genome wide
  • gene expression
  • dna methylation
  • poor prognosis
  • electronic health record
  • high resolution
  • big data
  • mass spectrometry
  • long non coding rna
  • binding protein
  • breast cancer risk