Particularities of Cataract Surgery in Elderly Patients: Corneal Structure and Endothelial Morphological Changes after Phacoemulsification.
Adela-Laura CiorbaAlin Cristian TeușdeaGeorge RoiuDaniela Simona CavaluPublished in: Geriatrics (Basel, Switzerland) (2024)
The aim of this study was to evaluate the influence of ultrasounds used in phacoemulsification during cataract surgery on the corneal structure and morphology in patients over 65 years. We compared the outcomes of phacoemulsification techniques in terms of corneal cell morphology in 77 patients over 65 years old and 43 patients under 65 years old. Corneal cell density, central corneal thickness and hexagonality were measured preoperatively and post-surgery (at 1 and 4 weeks) by specular microscopy. The effect of gender, axial length and anterior chamber depth on the parameters of corneal endothelium were evaluated. In both groups, a progressive decrease in endothelial cells was observed, starting from the first week post-surgery until the fourth postoperative week. The central corneal thickness increased in both groups with maximum values at the first week postoperatively, while their initial values were restored in the fourth week post-surgery, with no statistical difference between groups. Statistically significant differences were noticed in terms of cell hexagonality in the group over 65, showing smaller hexagonality at all preoperative and postoperative time points compared to group under 65. Our result highlights the importance of routine specular microscopy performed before surgery, regardless the age of the patients, with caution and careful attention to the phaco power intensity, ultrasound energy consumption and intraoperative manipulation of instruments, as well as proper use of viscoelastic substances to reduce corneal endothelium damage, especially in elderly patients.
Keyphrases
- cataract surgery
- optical coherence tomography
- end stage renal disease
- minimally invasive
- ejection fraction
- endothelial cells
- chronic kidney disease
- newly diagnosed
- wound healing
- peritoneal dialysis
- coronary artery bypass
- patients undergoing
- nitric oxide
- high resolution
- multiple sclerosis
- randomized controlled trial
- oxidative stress
- prognostic factors
- stem cells
- patient reported outcomes
- cell therapy
- mental health
- high throughput
- mesenchymal stem cells
- single molecule
- study protocol
- high glucose
- patient reported
- atrial fibrillation
- clinical practice
- adipose tissue
- preterm birth
- surgical site infection