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A novel transgenic mouse line with hippocampus-dominant and inducible expression of truncated human tau.

Yang GaoYuying WangHuiyang LeiZhendong XuShihong LiHaitao YuJiazhao XieZhentao ZhangGongping LiuYao ZhangJie ZhengJian-Zhi Wang
Published in: Translational neurodegeneration (2023)
This study developed a well-characterized and easy-to-use tool for the investigations and drug development for AD and other tauopathies.
Keyphrases
  • endothelial cells
  • poor prognosis
  • induced pluripotent stem cells
  • cerebrospinal fluid
  • prefrontal cortex