Understanding of interaction (subgroup) analysis in clinical trials.

Milos BrankovicIsabella KardysEwout Willem SteyerbergStanley LemeshowMaja MarkovicDimitris RizopoulosEric Boersma

Published in: European journal of clinical investigation (2019)

Altogether, this article provides a brief non-statistical guide for clinical investigators on how to perform, interpret and report interaction (subgroup) analyses in RCTs.

Keyphrases

clinical trial
phase iii
randomized controlled trial
study protocol
placebo controlled