Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer's disease.

Zhiqi SongYajin QuYanfeng XuLing ZhangLi ZhouYunlin HanWenjie ZhaoPin YuYu ZhangXianglei LiChuan Qin

Published in: Animal models and experimental medicine (2021)

Urinary exosomal miRNAs showing differences in expression prior to Aβ-plaque deposition were identified. These exosomal miRNAs represent potential noninvasive biomarkers that may be used to prevent AD in clinical applications.

Keyphrases

mouse model
poor prognosis
mesenchymal stem cells
stem cells
coronary artery disease
cognitive decline
single cell
human health
risk assessment
mild cognitive impairment