Hematologic analysis for hospitalized and outpatients infected by SARS-CoV-2 and possible use as a prognostic biomarker.

The SARS-CoV-2 infection is a global health problem; this has caused thousands of deaths around the world; this infection induces hematologic alterations and is necessary to recognize predictive biomarkers regarding the need for hospitalization or disease severity. This work aimed to analyze the different parameters in outpatients and hospitalized patients infected with SARS-CoV-2 and suggest that hematic biometry can be used for prognosis rapidly. We analyzed 689 patients of which 355 were outpatients (162 women and 193 men) and 334 required hospitalization (197 men and 137 women). The average age of hospitalized patients was 46 (men 49 and women 52), while the average age of outpatients was 49 (men 51 and women 44), the hematological parameters were analyzed and compared between outpatients and hospitalized patients and divided by age and sex. We found that in hospitalized patients, erythrocytes, hematocrit, and hemoglobin decreased while outpatients do not suffer changes in erythroid series. In leukocytes, these increased significantly, as well as neutrophils, but there was lymphocytopenia. In outpatients, we observed normal values of neutrophils and lymphopenia. We can conclude that hematic biometry can be used as a biomarker and the relation between neutrophils and lymphocytes is indicated for understanding the development of the disease and for the prognosis of the disease.