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Cabozantinib for the treatment of solid tumors: a systematic review.

Pablo M ReyCamillo PortaJaume CapdevilaAndrea B ApoloSantiago ViteriCristina Rodriguez-AntonaLidia MartinDaniel Castellano
Published in: Therapeutic advances in medical oncology (2022)
The identified evidence demonstrates the positive efficacy/effectiveness of cabozantinib monotherapy in various solid tumor types, with safety findings being consistent with those observed with other VEGFR-targeting tyrosine kinase inhibitors. When available, real-world findings were consistent with the data reported from clinical trials. A limitation of this review is the high proportion of abstracts; however, this allowed us to capture the most up-to-date findings.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • combination therapy
  • systematic review
  • open label
  • cancer therapy
  • replacement therapy
  • chronic myeloid leukemia