Applications of CRISPR-Cas9 in gynecological cancer research.
Wei ZhangYan LiuXing ZhouRong ZhaoHongbo WangPublished in: Clinical genetics (2020)
Gynecological cancers pose a significant threat to women's health worldwide, with cervical cancer, ovarian cancer, and endometrial cancer having high incidences. Current gynecological cancer treatment methods mainly include surgery, chemotherapy, radiotherapy, and chemoradiotherapy. The CRISPR-Cas9 gene editing technology as a new therapeutic method has shown tremendous effect in the treatment of other cancers, promoting research on its potential therapeutic effect in gynecological cancer. In this article, we reviewed the current research status of CRISPR-Cas9 technology in gynecological cancer, focusing on the importance of studying the mechanism of CRISPR-Cas9 in gynecological cancer treatment, thereby laying a foundation for further research on its clinical application.
Keyphrases
- crispr cas
- genome editing
- papillary thyroid
- endometrial cancer
- squamous cell
- locally advanced
- healthcare
- public health
- minimally invasive
- childhood cancer
- lymph node metastasis
- early stage
- squamous cell carcinoma
- radiation therapy
- pregnant women
- young adults
- polycystic ovary syndrome
- type diabetes
- social media
- climate change