Genotypic to Phenotypic Resistance Discrepancies Identified Involving β-Lactamase Genes, blaKPC, blaIMP, blaNDM-1, and blaVIM in Uropathogenic Klebsiella pneumoniae.
Umme Laila UrmiShamsun NaharMasud RanaFahmida SultanaNusrat JahanBillal HossainMohammed Shah AlamAbu Syed Md MosaddekJudy McKimmNor Azlina A RahmanMd Salequl IslamMainul HaquePublished in: Infection and drug resistance (2020)
The discrepancy of genotype and phenotype resistance has significant consequences for clinical bacteriology, precision in diagnosis, the prudent selection of antimicrobials, and rational prescribing. Heterogeneous phenotypes of antimicrobial susceptibility testing should be taken seriously to avoid inappropriate diagnostic and therapeutic decisions.