Exercise-induced increase in blood-based brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis: A systematic review and meta-analysis of exercise intervention trials.

Parnian ShobeiriAmirali KarimiSara MomtazmaneshAntônio Lúcio TeixeiraCharlotte E TeunissenErwin E H van WegenMark A HirschMir Saeed YekaninejadNima Rezaei

Published in: PloS one (2022)

This systematic review and meta-analysis shows that physical activity increases peripheral levels of BDNF in PwMS. More research on the effect of different modes of exercise on BDNF levels in PwMS is warranted.

Keyphrases

physical activity
multiple sclerosis
high intensity
stress induced
randomized controlled trial
resistance training
body mass index
chemotherapy induced