Irisin improves fatty acid oxidation and glucose utilization in type 2 diabetes by regulating the AMPK signaling pathway.

C XinJ LiuJ ZhangD ZhuH WangLi-Ze XiongY LeeJ YeK LianC XuL ZhangQ WangY LiuL Tao

Published in: International journal of obesity (2005) (2015)

Our results suggest that irisin has an essential role in glucose utilization and lipid metabolism, and irisin is a promising pharmacological target for the treatment of diabetes and its complications.

Keyphrases

type diabetes
fatty acid
glycemic control
signaling pathway
blood glucose
cardiovascular disease
skeletal muscle
insulin resistance
hydrogen peroxide
risk factors
adipose tissue
metabolic syndrome
oxidative stress
nitric oxide
replacement therapy
smoking cessation