S100A12 is involved in the pathology of osteoarthritis by promoting M1 macrophage polarization via the NF-κB pathway.
Yi ZhangZihua LiCheng ChenWang WeiZhendong LiHui HuangHaichao ZhouWenbao HeJiang XiaBing LiYunfeng Yang
Published in: Connective tissue research (2024)
This study demonstrated that S100A12 promotes M1 macrophage polarization through the NF-κB pathway, and found that LINC00894 has the potential to regulate the expression of S100A12 as a therapeutic approach.