A novel ADC targeting cell surface fibromodulin in a mouse model of triple-negative breast cancer.

Mozhan Haji GhaffariMiganoosh SimonianAli SalimiEbrahim MirzadeganNiloufar SadeghiMohammad-Reza NejadmoghaddamNasim EbrahimnezhadGhazaleh FazliRamina FatemiAli-Ahmad BayatMohammadali MazloomiHodjattallah Rabbani

Published in: Breast cancer (Tokyo, Japan) (2022)

Our results suggests high cell surface FMOD expression could be a novel bio-marker TNBCs. Furthermore, FMOD-ADC could be a promising candidate for targeting TNBCs.

Keyphrases

cell surface
mouse model
cancer therapy
poor prognosis
diffusion weighted imaging
diffusion weighted
drug delivery
binding protein
contrast enhanced
magnetic resonance