Circulating Insulin-Like Growth Factor 1 Levels and Migraine Risk: A Mendelian Randomization Study.

Reziya AbuduxukuerPeng-Peng NiuZhen-Ni GuoYu-Ming XuYi Yang

Published in: Neurology and therapy (2022)

This two-sample Mendelian randomization study showed that genetically determined increased IGF1 levels are causally associated with decreased migraine risk. Future randomized controlled trials are warranted to confirm the benefits of IGF1 administration on migraines.

Keyphrases

randomized controlled trial
clinical trial
growth hormone
pi k akt
cell proliferation
current status