INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10.

Wei ZhangJinjing ZhaoLin DengNestor IshimweJessica PauliWen WuShengshuai ShanWolfgang KempfMargaret D BallantyneDavid KimQing LyuMatthew BennettJulie RodorAdam W TurnerYao Wei LuPing GaoMihyun ChoiGanesh WarthiHa Won KimMargarida M BarrosoWilliam B BryantClint L MillerNeal L WeintraubLars MaegdefesselJoseph M MianoAndrew H BakerXiaochun Long

Published in: bioRxiv : the preprint server for biology (2023)

/MKL1/USP10 regulatory axis. Human BAC Tg mice offer a novel and physiologically relevant approach for investigating human-specific lncRNAs under vascular disease conditions.

Keyphrases

long noncoding rna
smooth muscle
endothelial cells
pluripotent stem cells
oxidative stress
type diabetes
transcription factor
metabolic syndrome
high fat diet induced