Topical glyceryl trinitrate (GTN) and eccentric exercises in the treatment of mid-portion achilles tendinopathy (the NEAT trial): a randomised double-blind placebo-controlled trial.
Paul D KirwanTrevor DuffyHelen P FrenchPublished in: British journal of sports medicine (2024)
Adding daily GTN ointment over 24 weeks to a 12-week eccentric exercise programme did not improve pain, function and activity level in patients with chronic mid-portion Achilles tendinopathy when compared with placebo ointment.
Keyphrases
- double blind
- placebo controlled
- study protocol
- resistance training
- phase iii
- clinical trial
- phase ii
- body composition
- high intensity
- open label
- platelet rich plasma
- randomized controlled trial
- physical activity
- rotator cuff
- chronic pain
- neuropathic pain
- pain management
- replacement therapy
- combination therapy
- gestational age
- wound healing
- smoking cessation