Vertebral Primary Bone Lesions: Review of Management Options.
Anjalika ChalamgariDaisy ValleXuban Palau VillarrealMarco ForemanAnnika LiuAashay PatelAkanksha DaveBrandon P Lucke-WoldPublished in: Current oncology (Toronto, Ont.) (2023)
The assessment and treatment of vertebral primary bone lesions continue to pose a unique yet significant challenge. Indeed, there exists little in the literature in the way of compiling and overviewing the various types of vertebral lesions, which can often have complicated intervention strategies. Given the severe consequences of mismanaged vertebral bone tumors-including the extreme loss of motor function-it is clear that such an overview of spinal lesion care is needed. Thus, in the following paper, we aim to address the assessment of various vertebral primary bone lesions, outlining the relevant nonsurgical and surgical interventional methods. We describe examples of primary benign and malignant tumors, comparing and contrasting their differences. We also highlight emerging treatments and approaches for these tumors, like cryoablation and stereotactic body radiation therapy. Ultimately, we aim to emphasize the need for further guidelines in regard to correlating lesion type with proper therapy, underscoring the innate diversity of vertebral primary bone lesions in the literature.
Keyphrases
- bone mineral density
- postmenopausal women
- body composition
- radiation therapy
- systematic review
- randomized controlled trial
- bone loss
- soft tissue
- immune response
- squamous cell carcinoma
- palliative care
- spinal cord
- climate change
- bone marrow
- clinical practice
- mesenchymal stem cells
- early onset
- rectal cancer
- smoking cessation