3D Computational Modeling of Blast Wave Transmission in Human Ear From External Ear to Cochlear Hair Cells: A Preliminary Study.

John BradshawMarcus BrownShangyuan Jiang Rong Z Gan

Published in: Military medicine (2024)

This microscale model is the first FE model of the OC to be connected to a macroscale model of the ear, forming a full multiscale ear model, and used to predict the OC's behavior under blast. Future work with this model will incorporate cochlear endolymphatic fluid, increase the number of OHC rows to 19 in total, and use the results of the model to reliably predict the sensorineural hearing loss resulting from blast exposure.

Keyphrases

endothelial cells
induced apoptosis
signaling pathway
hearing loss
endoplasmic reticulum stress
pluripotent stem cells