Neurotrophin growth factors and their receptors as promising blood biomarkers for Alzheimer's Disease: a gene expression analysis study.
Mohammad Reza AsadiJalal GharesouranHani SabaieMorteza Zaboli MahdiabadiSeyed Amirhossein MazhariMirmohsen Sharifi-BonabZeinab Shirvani-FarsaniMohammad TaheriArezou SayadMaryam RezazadehPublished in: Molecular biology reports (2024)
The observed decrease in the expression levels of NTRK2, TrkA, TrkC, and BDNF in AD patients, along with the identified associations between specific genes and their diagnostic capacity, indicate that these expressions have the potential to function as biomarkers for the diagnosis and treatment of AD.
Keyphrases
- genome wide identification
- end stage renal disease
- genome wide
- ejection fraction
- poor prognosis
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- risk assessment
- dna methylation
- gene expression
- transcription factor
- long non coding rna
- stress induced
- patient reported
- human health
- genome wide analysis
- bioinformatics analysis