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BarWare: efficient software tools for barcoded single-cell genomics.

Elliott SwansonJulian ReadingLucas T GrayPeter J Skene
Published in: BMC bioinformatics (2022)
BarWare is a modular set of tools linked by shell scripting: BarCounter, a computationally efficient barcode sequence quantification tool implemented in C; and BarMixer, an R package for identification of barcoded populations, merging barcoded data from multiple wells, and quality-control reporting related to scRNA-seq data. These tools and a self-contained implementation of the pipeline are freely available for non-commercial use at https://github.com/AllenInstitute/BarWare-pipeline .
Keyphrases
  • single cell
  • quality control
  • rna seq
  • electronic health record
  • big data
  • high throughput
  • healthcare
  • quality improvement
  • machine learning