Genistein attenuated gastric inflammation and apoptosis in Helicobacter pylori-induced gastropathy in rats.

Prasong SiriviriyakulDuangporn WerawatganonNisarat PhetnooKanjana SomanawatTanittha ChatsuwanNaruemon KlaikeawManeerat Chayanupatkul

Published in: BMC gastroenterology (2020)

Genistein exerted its gastroprotective effects through the reduction of pro-inflammatory mediators, nuclear receptor NF-κB expression and gastric mucosal apoptosis in rats with H. pylori-induced gastropathy.

Keyphrases

helicobacter pylori
oxidative stress
diabetic rats
high glucose
endoplasmic reticulum stress
cell cycle arrest
helicobacter pylori infection
cell death
poor prognosis
drug induced
signaling pathway
pi k akt
nuclear factor
lps induced
immune response
cell proliferation