Effectiveness of mRNA-1273 against delta, mu, and other emerging variants of SARS-CoV-2: test negative case-control study.

Katia J BruxvoortLina S SyLei QianBradley K AckersonYi LuoGina S LeeYun TianAna FloreaMichael AragonesJulia E TubertHarpreet S TakharJennifer H KuYamuna D PailaCarla A TalaricoHung Fu Tseng

Published in: BMJ (Clinical research ed.) (2021)

Two doses of mRNA-1273 were highly effective against all SARS-CoV-2 variants, especially against hospital admission with covid-19. However, vaccine effectiveness against infection with the delta variant moderately declined with increasing time since vaccination.

Keyphrases

sars cov
randomized controlled trial
copy number
respiratory syndrome coronavirus
systematic review
emergency department
binding protein
healthcare
coronavirus disease
gene expression
adverse drug
genome wide
drug induced