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Hsa-MiR-590-3p Promotes the Malignancy Progression of Pancreatic Ductal Carcinoma by Inhibiting the Expression of p27 and PPP2R2A via G1/S Cell Cycle Pathway.

Xiaoyang ShiWeiwei ShengChao JiaJingtong TangMing Dong
Published in: OncoTargets and therapy (2020)
MiR-590-3p promotes the proliferation, migration and invasion of pancreatic cancer cells. MiR-590-3p directly downregulated p27 and PPP2R2A and via the G1/S cell cycle pathway to promote the development of pancreatic cancer.
Keyphrases
  • cell cycle
  • cell proliferation
  • signaling pathway
  • poor prognosis
  • binding protein