Sex differences in gene expression with galactosylceramide treatment in Cln3Δex7/8 mice.

Joelle MakoukjiSally El-SittNadine J MakhoulJihane SoueidHumam KadaraRose-Mary N Boustany

Published in: PloS one (2020)

This study sheds light on global expression patterns following GalCer treatment of Cln3Δex7/8 mice. Understanding molecular effects of GalCer on mouse brain gene expression, paves the way for personalized strategies for treating this debilitating disease in humans.

Keyphrases

gene expression
dna methylation
poor prognosis
type diabetes
metabolic syndrome
adipose tissue
combination therapy
single molecule
wild type