Automated glycan assembly of highly branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius .
Narayana Murthy SabbavarapuPeter H SeebergerPublished in: Chemical communications (Cambridge, England) (2023)
Polysaccharides that are part of the human diet of fruits and vegetables influence the immune system via multiple signaling pathways. Given the immense complexity and diversity of naturally occurring polysaccharides and the difficulties associated isolating pure samples, few structure-activity relationships have been established. Rapid access to well-defined polysaccharides of biological relevance by automated glycan assembly (AGA) is important to create chemical tools to determine the link between nutritional oligo- and polysaccharides and the immune response. Here, we describe AGA of a hyper branched heptadecasaccharide repeating unit of arabinogalactan polysaccharide HH1-1 from Carthamus tinctorius .
Keyphrases
- water soluble
- immune response
- machine learning
- deep learning
- endothelial cells
- high throughput
- signaling pathway
- physical activity
- weight loss
- pi k akt
- dendritic cells
- induced pluripotent stem cells
- cell proliferation
- heavy metals
- inflammatory response
- oxidative stress
- pluripotent stem cells
- sensitive detection
- loop mediated isothermal amplification