Decreased prolyl hydroxylase 3 mRNA expression in oncocytomas compared with clear cell renal cell carcinoma.
Kampantais SpyridonIlias KounatidisVasiliki KotoulaIoannis VakalopoulosKonstantinos GkagkalidisGeorgios DimitriadisPublished in: The International journal of biological markers (2020)
To the best of our knowledge, this is the first time that the HIF/PHD pathway was compared between ccRCC and a common benign tumor, identifying the upregulation of PHD3 as the possible underlying factor guiding the difference in the behavior of ccRCC.