Pre-hospital freeze-dried plasma for critical bleeding after trauma: A pilot randomized controlled trial.

Biswadev MitraBen MeadleyStephen BernardMarc MaegeleRussell L GruenOlivia BradleyErica M WoodZoe K McQuiltenMark FitzgeraldToby St ClairAndrew WebbDavid AndersonMichael C Reade

Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2023)

This first reported experience of freeze-dried plasma use in Australia suggests pre-hospital administration is feasible. Given longer prehospital times typically associated with HEMS attendance, there is potential clinical benefit from this intervention and rationale for a definitive trial.

Keyphrases

study protocol
healthcare
clinical trial
randomized controlled trial
trauma patients
acute care
adverse drug
cardiac arrest
phase iii
atrial fibrillation
phase ii
double blind
emergency department
climate change