Topical preparations for the treatment of mild-to-moderate acne vulgaris: systematic review and network meta-analysis.

Beth L StuartE MaundC WilcoxKannan SridharanG SivaramakrishnanC RegasD NewellI SoulsbyK F TangAndrew Y FinlayH C BucherP LittleAlison Margaret Layton Miriam Santer

Published in: The British journal of dermatology (2021)

Adapalene in combination with BPO may be the most effective treatment for acne but with a slightly higher incidence of withdrawal than monotherapy. Inconsistent reporting of trial results precluded firmer conclusions.

Keyphrases

combination therapy
clinical trial
risk factors
emergency department
randomized controlled trial
open label
phase ii
adverse drug
wound healing