Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer.

Sung Wan KangOk-Ju KangJi-Young LeeHyejeong KimHunsoon JungHongjoong KimShin Wha LeeYong Man KimEun Kyung Choi

Published in: PloS one (2024)

The combination of ENB101-LNP, which inhibits E6/E7 of HPV 16, with cisplatin, demonstrated significant anticancer activity in the xenograft mouse model of cervical cancer.

Keyphrases

mouse model
high grade
cervical cancer screening
cancer therapy
fatty acid
oxide nanoparticles