Clinical performance of non-invasive prenatal testing for trisomies 21, 18 and 13 in twin pregnancies: A cohort study and a systematic meta-analysis.

Yuting HeYichong WangZhuyu LiHaitian ChenJiankai DengHao HuangXiaohong HeWentao ZengMin LiuBin HuangPeisong Chen

Published in: Acta obstetricia et gynecologica Scandinavica (2020)

The performance of NIPT for trisomy 21 in twin pregnancy was excellent and it was similar to that reported in singleton pregnancy. However, due to publication bias (trisomy 18) and small number of cases (trisomy 13), accurate assessment of the predictive performance of NIPT for trisomies 18 and 13 could not be achieved.

Keyphrases

preterm birth
systematic review
pregnancy outcomes
gestational age
pregnant women
meta analyses
birth weight
randomized controlled trial
physical activity
body mass index
weight loss