Transition-Metal-Free Unusual Oxidative Cleavage of Homoallylic Alcohol and Its Application in the Upcycling of Terpene to Value-Added Chemicals.

Tae Woo LeeJung Woon YangMonali DawangeYoung Kwang HanJung Woon Yang

Published in: ChemSusChem (2023)

A NaOtBu-O 2 -mediated oxidative dehomologation of homoallylic alcohols into structurally different carboxylic acids through direct oxidative cleavage of either the C(sp 2 )-C(sp 2 ) or C(sp 3 )-C(sp 3 ) bond utilizing enolate chemistry was demonstrated. Furthermore, under transition-metal-free conditions, this protocol has been applied to convert terpene as biomass feedstock into value-added chemicals.

Keyphrases

transition metal
randomized controlled trial
dna binding
wastewater treatment
drug discovery