Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer.

Chitra JosephMaariya ArshadSasagu KurozomiMaryam AlthobitiIslam M MiligySara Al-IzziMichael S TossFang Qin GohSimon J JohnstonStewart G MartinIan O EllisNigel P MonganAndrew R GreenEmad A Rakha

Published in: Breast cancer research and treatment (2018)

This study provides evidence for the prognostic value of CD133 in invasive BC. A strong positive association of BC stem cell markers is observed at the protein level. Further studies to assess the value of stem cell markers individually or in combination in BC is warranted.

Keyphrases

poor prognosis
stem cells
cancer stem cells
long non coding rna
cell proliferation
cell therapy
transcription factor
mesenchymal stem cells
small molecule
bone marrow